Musicians who have played at the Slippery Noodle include Luther Allison, Magic Dick, Jay Giles, John Mayall, Albert Collins, Buddy Miles, Charlie Musselwhite, Jr. Wells, Rick Derringer, Rare Earth, Lonnie Mack, Edgar Winter, Commander Cody, Savoy Brown, Matt "Guitar" Murphy, Jim Schwall, James Cotton, Big Head Todd and the Monsters, Yank Rachell, Larry Crane, Elvin Bishop, Duke Robillard, Pinetop Perkins, Country Joe McDonald, Ronnie Earl, Little Charlie and the Nightcats, Sugar Blue, The Nighthawks, Clarence "Gatemouth" Brown and Johnny Clyde Copeland to name a few.
Celebrities to visit the Slippery Noodle include Jimmy Fallon, Will Forte, Rick Reilly, Tim Tebow, Dan Aykroyd , John Corbett, Micky Dolenz, Dale Earnhardt Jr., Harrison Ford, Dave Matthews, The Blues Brothers Band, John Entwistle, Greg Kinnear, Danica Patrick, Bruce Smith, Matt LeBlanc, Jason Priestly, Billy Joel, Mudvayne, Michael Bolton, Mick Fleetwood, David Boreanaz, Lee Oskar, Michael Buble, Gene Simmons, Kid Rock, Tim Robbins, Neal McDonough, Mikey Teutul, Candlebox, Wendell (High Life), Mike Tomlin, Scott Rolen, Andy Roddick, Joe Montana, Dan Wheldon, Linda Gray, Brett Favre, Anthony Edwards, Patrick Dempsey, Alyson Hannigan, Jerry Stiller, Neil Diamond, Oasis, Steve Howe, Alan White, Robert DeNiro, Vince Neil, Hootie & the Blowfish, Cheap Trick, Jeff Healy, Greg Allman, Liza Minnelli, Stephen Stills, Johnny Rivers, Joe Ely, Carmen Appice, G.E. Smith of Saturday Night Live fame, Antone Figg (drummer for Paul Shaffer's band), Harry Connick, Jr., Spike Lee, Larry Drake, David Hasselhoff, Ernest Borgnine, Keb Mo', Walt Willy (Jack Montgomery from All My Children), Karl Malone, Kevin Call, Big Al, A.J. Foyt, Johnny Parsons, Sr., Dean Biasucci, Bobby Rahal, Ron Stark, Bill Cowher, Ron Myer, Digger Phelp and the list goes on and on.